MOTS -C (20mg)

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a mitochondria-derived peptide studied as a regulator of metabolic homeostasis through AMPK activation and nuclear translocation. This 20mg presentation is suited for moderate-duration research protocols requiring precise dosing and flexibility. Studies have highlighted its role as a potential exercise mimetic and insulin sensitizer.

Mechanism of Action

•        Activates AMPK signaling, studied for increases in glucose uptake in skeletal muscle independent of insulin.

•        Research indicates promotion of fatty acid oxidation and reduction of ectopic lipid accumulation.

•        Investigated for nuclear translocation under metabolic stress, modulating gene expression in antioxidant and bioenergetics pathways.

•        Studies show modulation of the folate-methionine cycle for optimization of one-carbon metabolism.

Research Areas

•        Insulin resistance reversal and glucose metabolism research.

•        Body composition studies in metabolic disease models.

•        Physical endurance research as an exercise mimetic.

•        Longevity biology through mitochondrial function studies.

Presentation and Storage

Supplied as a lyophilized powder in a sealed vial containing 20mg of MOTS-c. Reconstitute with bacteriostatic water for laboratory use. Store at -20C.