MOTS -C (40mg)

MOTS-c is a mitochondria-encoded peptide studied as a powerful metabolic regulator. Under cellular stress conditions, it translocates from mitochondria to the nucleus where it activates AMPK pathways and influences insulin sensitivity, fatty acid metabolism, and cellular stress responses. This 40mg presentation supports extended multi-phase research protocols.

Mechanism of Action

•        Activates AMPK (AMP-activated protein kinase), studied for its role in glucose uptake and fatty acid oxidation in metabolic models.

•        Research indicates inhibition of the folate cycle and de novo purine synthesis in conditions of metabolic overload.

•        Investigated for nuclear translocation under stress, modulating gene expression related to mitochondrial biogenesis and antioxidant defense.

•        Preclinical studies suggest promotion of insulin sensitization in skeletal muscle and adipose tissue.

•        Displays anti-inflammatory effects relevant to metabolic and age-related inflammatory research models.

Research Areas

•        Insulin resistance and type 2 diabetes research with measurable improvements in glucose metabolism markers.

•        Obesity and metabolic syndrome studies through enhanced energy expenditure models.

•        Anti-aging and exercise mimetic research targeting longevity pathways.

•        Athletic performance biology and endurance research.

•        Muscle preservation studies in caloric restriction or sarcopenia models.

Presentation and Storage

Supplied as a lyophilized powder in a sealed vial containing 40mg of MOTS-c. Reconstitute with bacteriostatic water for laboratory use. Store at -20C.