SELANK

Selank is a synthetic heptapeptide analog of the endogenous immunomodulatory peptide Tuftsin (Thr-Lys-Pro-Arg), developed by the Institute of Molecular Genetics of the Russian Academy of Sciences. It has been studied for its anxiolytic, nootropic, and immunomodulatory properties. Research suggests it produces anti-anxiety effects in animal models without sedation, tolerance development, or dependency.

Mechanism of Action

•        Studied for modulation of GABA-A receptor sensitivity and influence on serotonin, dopamine, and enkephalin signaling without receptor downregulation.

•        Research shows increases in BDNF (brain-derived neurotrophic factor) levels, supporting neuroplasticity and memory research.

•        Investigated for stabilization of enkephalin metabolism, extending the activity of endogenous neuropeptides in brain tissue.

•        Preclinical studies show enhancement of T-helper cell activity and interleukin expression in immune biology models.

•        Studied for reduction of stress-induced cortisol elevation through HPA axis modulation.

Research Areas

•        Anxiety and stress response research in preclinical models.

•        Cognitive biology studies including memory, focus, and learning capacity under stress conditions.

•        Immune modulation research in models of chronic psychosocial stress.

•        Depression and mood regulation biology.

•        Sleep and serotonergic pathway research.

Presentation and Storage

Supplied as a lyophilized powder in a sealed vial containing 10mg of Selank. Reconstitute with bacteriostatic water for laboratory use. Store at -20C.