NAD+ (1000mg)
Nicotinamide adenine dinucleotide (NAD+) is a critical coenzyme involved in hundreds of cellular metabolic reactions. It plays a central role in energy production, DNA repair, gene expression regulation, and cellular aging. NAD+ levels decline with age, and preclinical research has linked this decline to mitochondrial dysfunction and impaired cellular repair mechanisms. This 1000mg presentation supports high-load or multi-subject research protocols.
Mechanism of Action
• Functions as an essential cofactor in the electron transport chain, enabling mitochondrial ATP production.
• Research shows activation of sirtuins (SIRT1-7), key regulators of gene expression, DNA repair, and metabolic homeostasis.
• Activates PARP enzymes involved in DNA strand break repair, studied in models of genome instability.
• Modulates CD38 and NAMPT pathways, which regulate NAD+ synthesis and recycling.
• Preclinical studies suggest a role in circadian rhythm regulation through NAD+-dependent transcription factor activity.
Research Areas
• Cellular energy restoration and mitochondrial function research in aging models.
• Neuroprotection and cognitive support research through mitochondrial pathway analysis.
• Metabolic health studies including insulin sensitivity and mitochondrial biogenesis.
• Cardiac resilience and cardiovascular biology research.
• Fatigue and post-viral cellular recovery studies.
Presentation and Storage
Supplied as a lyophilized powder in a sealed vial containing 1000mg of NAD+. Reconstitute with sterile or bacteriostatic water for research use. Store at -20C.