KISSPEPTIN (5mg)

Kisspeptin (formerly metastin) is a neuropeptide encoded by the KISS1 gene and studied as a critical upstream regulator of the hypothalamic-pituitary-gonadal (HPG) axis. By stimulating GnRH neurons, it drives pulsatile LH and FSH release, making it a foundational research compound in reproductive endocrinology and hormone biology.

Mechanism of Action

•        Binds to the kisspeptin receptor (KISS1R/GPR54) on GnRH neurons in the hypothalamus, triggering pulsatile GnRH secretion in animal models.

•        Research shows downstream stimulation of LH and FSH from the anterior pituitary, supporting gonadal steroidogenesis.

•        Investigated for its role in pubertal onset and reproductive axis maintenance.

•        Studied for modulation of estrogen and progesterone feedback loops in female reproductive biology.

•        Preclinical research suggests influence on sexual behavior and libido through central neurological pathways.

Research Areas

•        Hypogonadism and testosterone biology research.

•        Fertility and reproductive cycle regulation studies.

•        Hypothalamic amenorrhea and reproductive axis restoration models.

•        HPG axis stimulation research as an alternative to HCG-based approaches.

•        Puberty regulation and reproductive aging biology.

Presentation and Storage

Supplied as a lyophilized powder in a sealed vial containing 5mg of kisspeptin. Reconstitute with bacteriostatic water for laboratory use. Store at -20C.