SERMORELIN

Sermorelin is a synthetic analog of growth hormone-releasing hormone (GHRH), comprising its first 29 biologically active amino acids. Studied as a physiological secretagogue, it stimulates endogenous pituitary GH production rather than replacing it exogenously, preserving the natural feedback regulation of the somatotropic axis in research models.

Mechanism of Action

•        Binds to GHRH receptors on anterior pituitary somatotrophs, triggering GH synthesis and secretion in preclinical studies.

•        Maintains endogenous GH pulsatility in research models, supporting downstream IGF-1 production in the liver.

•        Investigated for preservation of hypothalamic-pituitary feedback sensitivity compared to direct GH administration.

•        Studied for gradual, physiological GH elevation relevant to body composition, sleep, and cellular repair research.

Research Areas

•        GH deficiency and adult somatopause biology.

•        Anti-aging research including muscle mass maintenance, fat reduction, and skin quality studies.

•        Sleep quality and nocturnal GH secretion biology.

•        Metabolic and energy homeostasis research.

•        Injury recovery biology through IGF-1 pathway analysis.

Presentation and Storage

Supplied as a lyophilized powder in a sealed vial containing 10mg of sermorelin. Reconstitute with bacteriostatic water for laboratory use. Store at -20C.